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iron (III) isomaltoside 1000 (Diafer)

Advice

following a resubmission:

iron III isomaltoside 1000 5% (Diafer®) is accepted for use within NHS Scotland.

Indication under review: For the treatment of iron deficiency in adults with chronic kidney disease (CKD) on dialysis, when oral iron preparations are ineffective or cannot be used. 

Iron III isomaltoside 1000 at a higher (10%) concentration has been shown to be non-inferior to another intravenous iron product in maintaining haemoglobin concentration in adult patients with CKD who are iron deficient and are receiving haemodialysis. 

This SMC advice takes account of the benefits of a Patient Access Scheme (PAS) that improves the cost-effectiveness of iron III isomaltoside 1000 5%. This advice is contingent upon the continuing availability of the PAS in NHS Scotland or a list price that is equivalent or lower.

Drug Details

Drug Name: iron (III) isomaltoside 1000 (Diafer)
SMC Drug ID: 1177/16
Manufacturer: Pharmacosmos UK
Indication: For the treatment of iron deficiency in adults with chronic kidney disease (CKD) on dialysis, when oral iron preparations are ineffective or cannot be used.
BNF Category:
Sub Category: 9.1 Anaemias and some other blood disorders
Submission Type: Resubmission
Status: Accepted
Date Advice Published: 13 February 2017

Archived Advice

Full submission 12 September 2016

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