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botulinum toxin A (Botox)

Advice

following a resubmission:

botulinum toxin A (Botox®) is accepted for restricted use within NHS Scotland.

Indication under review: Prophylaxis of headaches in adults with chronic migraine (headaches on at least 15 days per month of which at least 8 days are with migraine).

SMC restriction: use in adults with chronic migraine whose condition has failed to respond to ≥3 prior oral prophylactic treatments, where medication overuse has been appropriately managed.

In pooled analysis of the two pivotal phase III studies, botulinum toxin type A (Botox®) significantly reduced the frequency of headache days compared with placebo.

Drug Details

Drug Name: botulinum toxin A (Botox)
SMC Drug ID: 692/11
Manufacturer: Allergan Ltd
Indication: Prophylaxis of headaches in adults with chronic migraine (headaches on at least 15 days per month of which at least 8 days are with migraine).
BNF Category:
Sub Category: 4.9 Drugs used in Parkinsonism and related disorders
Submission Type: Resubmission
Status: Restricted
Date Advice Published: 13 February 2017

Archived Advice

Resubmission 8 April 2013
Full submission 10 April 2011

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