botulinum toxin A (Botox)
following a resubmission:
botulinum toxin A (Botox®) is accepted for restricted use within NHS Scotland.
Indication under review: Prophylaxis of headaches in adults with chronic migraine (headaches on at least 15 days per month of which at least 8 days are with migraine).
SMC restriction: use in adults with chronic migraine whose condition has failed to respond to ≥3 prior oral prophylactic treatments, where medication overuse has been appropriately managed.
In pooled analysis of the two pivotal phase III studies, botulinum toxin type A (Botox®) significantly reduced the frequency of headache days compared with placebo.
|Drug Name:||botulinum toxin A (Botox)|
|SMC Drug ID:||692/11|
|Indication:||Prophylaxis of headaches in adults with chronic migraine (headaches on at least 15 days per month of which at least 8 days are with migraine).|
|Sub Category:||4.9 Drugs used in Parkinsonism and related disorders|
|Date Advice Published:||13 February 2017|
|botulinum toxin type a (Botox)||Resubmission||8 April 2013|
|botulinum toxin type a (Botox)||Full submission||10 April 2011|