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SMC ID Date Medicine Submission Type Indication
SMC2769 10/03/2025 atezolizumab (Tecentriq) Non submission

As monotherapy for the first-line treatment of adult patients with advanced NSCLC who are ineligible for platinum-based therapy.

SMC2492 08/08/2022 atezolizumab (Tecentriq) Full

Monotherapy as adjuvant treatment following complete resection for adult patients with Stage II to IIIA (7th edition of the Union for International Cancer Control (UICC)/ American Joint Committee on Cancer (AJCC) - staging system) non-small cell lung cancer (NSCLC) whose tumours have PD-L1 expression on ≥50% of tumour cells (TC) and whose disease has not progressed following platinum-based adjuvant chemotherapy.

SMC2379 08/11/2021 atezolizumab (Tecentriq) Full

As monotherapy is indicated for the first-line treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumours have a PD-L1 expression ≥ 50% tumour cells (TC) or ≥ 10% tumour-infiltrating immune cells (IC) and who do not have epidermal growth factor receptor (EGFR) mutant or anaplastic lymphoma kinase (ALK)-positive NSCLC.

SMC2349 12/07/2021 atezolizumab (Tecentriq) Full

In combination with bevacizumab for the treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have not received prior systemic therapy.

SMC2279 09/11/2020 atezolizumab (Tecentriq) Full

In combination with carboplatin and etoposide, is indicated for the first-line treatment of adult patients with extensive-stage small cell lung cancer.

SMC2267 09/11/2020 atezolizumab (Tecentriq) Full

In combination with nab-paclitaxel for the treatment of adult patients with unresectable locally advanced or metastatic triple-negative breast cancer (TNBC) whose tumours have PD-L1 expression ≥  1% and who have not received prior chemotherapy for metastatic disease.

SMC2254 09/12/2019 atezolizumab (Tecentriq) Non submission

In combination with nab-paclitaxel and carboplatin for the first-line treatment of adult patients with metastatic non-squamous non-small cell lung cancer (NSCLC) who do not have EGFR mutant or ALK-positive NSCLC.

SMC2208 11/11/2019 atezolizumab (Tecentriq) Full

In combination with bevacizumab, paclitaxel and carboplatin, is indicated for the first-line treatment of adult patients with metastatic non-squamous non‑small cell lung cancer (NSCLC). In patients with EGFR mutant or ALK-positive NSCLC, atezolizumab, in combination with bevacizumab, paclitaxel and carboplatin, is indicated only after failure of appropriate targeted therapies.

SMC2103 12/11/2018 atezolizumab (Tecentriq) Full As monotherapy for the treatment of adult patients with locally advanced or metastatic urothelial carcinoma: − after prior platinum-containing chemotherapy, or − who are considered cisplatin ineligible
1336/18 09/07/2018 atezolizumab (Tecentriq) for NSCLC Full Treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) after prior chemotherapy. Patients with EGFR activating mutations or ALK-positive tumour mutations should also have received targeted therapy before receiving Tecentriq.
1297/18 12/03/2018 atezolizumab (Tecentriq) Full As monotherapy, indicated for the treatment of adult patients with locally advanced or metastatic urothelial carcinoma after prior platinum - containing chemotherapy or who are considered cisplatin ineligible.

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