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SMC ID Date Medicine Submission Type Indication
SMC2673 07/10/2024 selinexor (Nexpovio) Full

In combination with dexamethasone for the treatment of multiple myeloma in adult patients who have received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, two immunomodulatory agents and an anti-CD38 monoclonal antibody, and who have demonstrated disease progression on the last therapy.

SMC2484 11/04/2022 carfilzomib (Kyprolis) Non submission

In combination with daratumumab and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.

SMC2423 11/10/2021 isatuximab (Sarclisa) Non submission

in combination with carfilzomib and dexamethasone, for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.

SMC2290 12/10/2020 carfilzomib (Kyprolis) Resubmission

In combination with lenalidomide and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy

1242/17 07/08/2017 carfilzomib (Kyprolis) Full in combination with dexamethasone alone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.

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