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SMC ID Date Medicine Submission Type Indication
SMC2842 11/05/2026 enfortumab vedotin (Padcev) Full

In combination with pembrolizumab for the first-line treatment of adult patients with unresectable or metastatic urothelial cancer who are eligible for platinum-containing chemotherapy.

SMC2505 11/07/2022 enfortumab vedotin (Padcev) Non submission

As monotherapy for the treatment of adult patients with locally advanced or metastatic urothelial cancer who have previously received a platinum-containing chemotherapy and a programmed death receptor 1 or programmed death ligand 1 inhibitor.

Publication due date SMC meeting date Medicine Submission Type Indication
TBC TBC pembrolizumab (Keytruda) Full

in combination with enfortumab vedotin, as neoadjuvant treatment and then continued after radical cystectomy as adjuvant treatment, is indicated for the treatment of adults with muscle invasive bladder cancer (MIBC).