Advice

Following a full resubmission

Adefovir dipivoxil (Hepsera) is accepted for restricted use within NHS Scotland for the treatment of chronic hepatitis B in adults with either compensated liver disease with evidence of active viral replication, persistently elevated serum alanine aminotransferase (ALT) levels and histological evidence of active liver inflammation and fibrosis, or decompensated liver disease. Its use is restricted to patients who demonstrate lamivudine resistance.

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Medicine details

Medicine name:
Adefovir dipivoxil (Hepsera®)
SMC ID:
54/03
Indication:

Chronic hepatitis B

Pharmaceutical company
Gilead Sciences Ltd
BNF chapter
Infections
Submission type
Resubmission
Status
Restricted
Date advice published
09 May 2005