Advice

following a full submission

aripiprazole prolonged release suspension for injection (Abilify Maintena®) is accepted for use within NHS Scotland.

Indication under review: maintenance treatment of schizophrenia in adult patients stabilised with oral aripiprazole.

In a comparative study, aripiprazole prolonged release suspension for injection was as effective as oral aripiprazole in reducing the risk of impending relapse over 26 weeks in stabilised schizophrenic patients.  Weaknesses in the indirect comparison limit the reliability of relative efficacy and safety with prolonged release injection forms of other atypical antipsychotics. 

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Medicine details

Medicine name:
aripiprazole (Abilify)
SMC ID:
962/14
Indication:
Maintenance treatment of schizophrenia in adult patients stabilised with oral aripiprazole.
Pharmaceutical company
Otsuka Pharmaceutical Europe
BNF chapter
Central nervous system
Submission type
Full
Status
Accepted
Date advice published
12 May 2014