Advice

following a full submission assessed under the end of life process:

avelumab (Bavencio®) is accepted for use within NHSScotland.

Indication under review: in combination with axitinib for the first-line treatment of adult patients with advanced renal cell carcinoma (RCC).

Avelumab plus axitinib, compared with a vascular endothelial growth factor (VEGF)-targeting tyrosine-kinase inhibitor (TKI), improved progression-free survival in adults with advanced RCC.

This advice applies only in the context of an approved NHSScotland Patient Access Scheme (PAS) arrangement delivering the cost-effectiveness results upon which the decision was based, or a PAS/ list price that is equivalent or lower.

This advice takes account of views from a Patient and Clinician Engagement (PACE) meeting.

Medicine details

Medicine name:
avelumab (Bavencio)
SMC ID:
SMC2248
Indication:

In combination with axitinib is indicated for the first-line treatment of adult patients with advanced renal cell carcinoma (RCC).

Pharmaceutical company
Merck
BNF chapter
Malignant disease and immunosuppression
Submission type
Full
Status
Accepted
Date advice published
12 October 2020