Following a full submission
bivalirudin (Angiox) is accepted for restricted use within NHS Scotland for the treatment of adult patients with acute coronary syndromes (unstable angina/non-ST segment elevation myocardial infarction) planned for urgent or early intervention. It is restricted to use in patients who would otherwise have been considered for heparin in combination with a glycoprotein IIb/IIIa antagonist. In these patients bivalirudin monotherapy may be a suitable alternative. It should not be used as an alternative to heparin alone.
Bivalirudin should be administered with aspirin and clopidogrel.
Bivalirudin showed a reduced risk of bleeding compared to a heparin-based anticoagulant strategy in patients with moderate and high risk acute coronary syndromes undergoing early invasive management.
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Medicine details
- Medicine name:
- bivalirudin (Angiox)
- SMC ID:
- 516/08
- Indication:
- Acute coronary syndromes
- Pharmaceutical company
- The Medicines Company
- BNF chapter
- Cardiovascular system
- Submission type
- Full
- Status
- Restricted
- Date advice published
- 08 December 2008