Advice

following a full submission:

caffeine citrate (Peyona®) is accepted for use within NHS Scotland.

Indication under review: treatment of primary apnoea of premature newborns.

In premature infants with apnoea of prematurity, caffeine citrate significantly reduced apnoeic episodes compared with placebo.  A long-term placebo-controlled study demonstrated a reduced risk of disabilities relevant to these infants.

This SMC advice takes account of the benefits of a Patient Access Scheme (PAS) that improves the cost-effectiveness of caffeine citrate (Peyona®).  This SMC advice is contingent upon the continuing availability of the PAS or an equivalent or lower list price in NHS Scotland.

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Medicine details

Medicine name:
caffeine Citrate 20mg/ml solution for infusion and oral solution (Peyona)
SMC ID:
814/12
Indication:
Treatment of primary apnoea of premature newborns.
Pharmaceutical company
Chiesi Limited
BNF chapter
Respiratory system
Submission type
Full
Status
Accepted
Date advice published
09 September 2013