Advice

in the absence of a submission from the holder of the marketing authorisation

canakinumab (Ilaris ®) is not recommended for use within NHS Scotland.

Indication under review: Treatment of the following autoinflammatory periodic fever syndromes in adults, adolescents and children aged 2 years and older:

  • tumour necrosis factor  receptor associated periodic syndrome
  • hyperimmunoglobulin D syndrome / mevalonate kinase deficiency
  • Familial Mediterranean Fever

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication.  As a result we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
canakinumab (Ilaris)
SMC ID:
1268/17
Indication:
treatment of the following autoinflammatory periodic fever syndromes in adults, adolescents and children aged 2 years and older: •tumour necrosis factor receptor associated periodic syndrome •hyperimmunoglobulin D syndrome / mevalonate kinase deficiency •Familial Mediterranean Fever
Pharmaceutical company
Novartis Pharmaceuticals UK Ltd
BNF chapter
Musculoskeletal and joint diseases
Submission type
Non submission
Status
Not recommended
Date advice published
07 August 2017