Advice

in the absence of a submission from the holder of the marketing authorisation:

ceritinib (Zykadia®) is not recommended for use within NHS Scotland.

Indication under review: As monotherapy for the first-line treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer.

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this setting. As a result we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
ceritinib (Zykadia)
SMC ID:
1333/18
Indication:
As monotherapy for the first-line treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer.
Pharmaceutical company
Novartis Pharmaceuticals UK Ltd
BNF chapter
Malignant disease and immunosuppression
Submission type
Non submission
Status
Not recommended
Date advice published
09 April 2018