Advice
in the absence of a submission from the holder of the marketing authorisation:
cinacalcet hydrochloride granules in capsules for opening (Mimpara®) is not recommended for use within NHSScotland.
Indication under review:
Secondary hyperparathyroidism (HPT)
- Treatment of secondary HPT in adult patients with end-stage renal disease (ESRD) on maintenance dialysis therapy
- Treatment of secondary HPT in children aged 3 years and older with ESRD on maintenance dialysis therapy in whom secondary HPT is not adequately controlled with standard of care therapy
Parathyroid carcinoma and primary HPT in adults
- Reduction of hypercalcaemia in adult patients with:
- parathyroid carcinoma
- primary HPT for whom parathyroidectomy would be indicated on the basis of serum calcium levels (as defined by relevant treatment guidelines), but in whom parathyroidectomy is not clinically appropriate or is contraindicated
The holder of the marketing authorisation has not made a submission to SMC regarding this product in these indications. As a result we cannot recommend its use within NHSScotland.
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Medicine details
- Medicine name:
- cinacalcet hydrochloride (Mimpara)
- SMC ID:
- SMC2275
- Indication:
Secondary hyperparathyroidism (HPT)
- Treatment of secondary HPT in adult patients with end-stage renal disease (ESRD) on maintenance dialysis therapy.
- Treatment of secondary HPT in children aged 3 years and older with ESRD on maintenance dialysis therapy in whom secondary HPT is not adequately controlled with standard of care therapy.
Parathyroid carcinoma and primary HPT in adults
- Reduction of hypercalcaemia in adult patients with:
- parathyroid carcinoma
- primary HPT for whom parathyroidectomy would be indicated on the basis of serum calcium levels (as defined by relevant treatment guidelines), but in whom
parathyroidectomy is not clinically appropriate or is contraindicated
- Pharmaceutical company
- Amgen Ltd
- Submission type
- Non submission
- Status
- Not recommended
- Date advice published
- 09 March 2020