Advice

Following a full submission

Conjugated oestrogen 0.3mg, medroxyprogesterone 1.5mg (Premique Low Dose) is accepted for use within NHS Scotland as hormone replacement therapy (HRT) for oestrogen deficiency symptoms in postmenopausal women with an intact uterus.

It is effective in controlling vasomotor symptoms and is associated with lower rates of breast pain and endometrial bleeding compared to other products with higher oestrogen content. It is more expensive than several other HRT therapies, but less expensive than the current market leader in Scotland.

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Medicine details

Medicine name:
Conjugated oestrogen medroxyprogesterone (Premique Low Dose®)
SMC ID:
130/04
Indication:
Hormone replacement therapy for oestrogen deficiency symptoms in postmenopausal women with an intact uterus
Pharmaceutical company
Wyeth Pharmaceuticals
BNF chapter
Endocrine system
Submission type
Full
Status
Accepted
Date advice published
08 November 2004