Advice

Following a full submission

darifenacin (Emselex®) is accepted for restricted use within NHS Scotland for the symptomatic treatment of urge incontinence and/or increased urinary frequency and urgency as may occur in patients with overactive bladder syndrome.

Darifenacin is effective in reducing symptoms associated with overactive bladder, including frequency, urgency and incontinence and the treatment effect is similar to another antimuscarinic. Darifenacin is associated with adverse effects typical of antimuscarinic agents used in this condition. It is restricted to second line use as there are cheaper antimuscarinics available that would normally be used as first-line agents.

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Medicine details

Medicine name:
darifenacin 7.5 mg, 15 mg prolonged-release tablets(Emselex)
SMC ID:
377/07
Indication:
Urge incontinence
Pharmaceutical company
Ardana Bioscience
BNF chapter
Obstetrics, gynaecology, and urinary-tract disorders
Submission type
Full
Status
Restricted
Date advice published
11 June 2007