following a full submission:
defatted powder of Arachis hypogaea L, semen (Palforzia®) is not recommended for use within NHSScotland.
Indication under review: treatment of patients aged 4 to 17 years with a confirmed diagnosis of peanut allergy. Palforzia® may be continued in patients 18 years of age and older. Palforzia® should be used in conjunction with a peanut-avoidant diet.
Palforzia®, compared with placebo, increased the proportion of patients aged 4 to 17 years with peanut allergy who could tolerate, with no more than mild symptoms, a single dose of at least 1,000mg peanut protein (2,043mg cumulative).
The submitting company did not present a sufficiently robust economic analysis to gain acceptance by SMC.
The submitting company has indicated their intention to make a resubmission.
Download detailed advice810KB (PDF)
Medicine details
- Medicine name:
- defatted powder of Arachis hypogaea L, semen (peanuts) (Palforzia)
- SMC ID:
- SMC2487
- Indication:
Treatment of patients aged 4 to 17 years with a confirmed diagnosis of peanut allergy. Palforzia may be continued in patients 18 years of age and older.
- Pharmaceutical company
- Aimmune Therapeutics
- BNF chapter
- Immunological products and vaccines
- Submission type
- Full
- Status
- Not recommended
- Date advice published
- 10 October 2022