Advice

following a full submission:

deferasirox (Exjade®) is accepted for restricted use within NHS Scotland for the treatment of chronic iron overload associated with the treatment of rare acquired or inherited anaemias requiring recurrent blood transfusions. It is not recommended for patients with myelodysplastic syndromes.

Patients with myelodysplastic syndromes, the commonest cause of transfusion-dependent anaemia, were poorly represented in the clinical trial population and the economic case was not demonstrated in this group.

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Medicine details

Medicine name:
deferasirox (Exjade)
SMC ID:
347/07
Indication:
Chronic iron overload associated with the treatment of rare acquired or inherited anaemias requiring recurrent blood transfusions
Pharmaceutical company
Novartis Pharmaceuticals UK Ltd
BNF chapter
Nutrition and blood
Submission type
Full
Status
Restricted
Date advice published
12 February 2007