Advice

In the absence of a submission from the holder of the marketing authorisation:

deferasirox (Exjade®) is not recommended for use within NHS Scotland.

Indication under review: treatment of chronic iron overload requiring chelation therapy when deferoxamine therapy is contraindicated or inadequate in patients with non-transfusion-dependent thalassaemia syndromes aged 10 years and older.

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication.  As a result we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
deferasirox (Exjade)
SMC ID:
866/13
Indication:
Treatment of chronic iron overload requiring chelation therapy when deferoxamine therapy is contraindicated or inadequate in patients with non-transfusion-dependent thalassaemia syndromes aged 10 years and older.
Pharmaceutical company
Novartis Pharmaceuticals UK Ltd
BNF chapter
Nutrition and blood
Submission type
Non submission
Status
Not recommended
Date advice published
08 April 2013