Advice

 in the absence of a submission from the holder of the marketing authorisation

denosumab (Xgeva®) is not recommended for use within NHS Scotland.

Indication under review: Adults and skeletally mature adolescents with giant cell tumour of bone that is unresectable or where surgical resection is likely to result in severe morbidity

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication.  As a result we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
denosumab (Xgeva)
SMC ID:
1119/15
Indication:
Adults and skeletally mature adolescents with giant cell tumour of bone that is unresectable or where surgical resection is likely to result in severe morbidity
Pharmaceutical company
Amgen Ltd
BNF chapter
Endocrine system
Submission type
Non submission
Status
Not recommended
Date advice published
07 December 2015