Advice

in the absence of a submission from the holder of the marketing authorisation:

dupilumab (Dupixent®) is not recommended for use within NHSScotland.

Indication under review: treatment of chronic spontaneous urticaria (CSU) in patients aged 12 years and older whose disease is not adequately controlled with H1 antihistamine treatment.

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result, we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
dupilumab (Dupixent)
SMC ID:
SMC2896
Indication:

Treatment of chronic spontaneous urticaria (CSU) in patients aged 12 years and older whose disease is not adequately controlled with H1 antihistamine treatment.

Pharmaceutical company
Sanofi
BNF chapter
Skin
Submission type
Non submission
Status
Not recommended
Date advice published
19 January 2026