Advice

in the absence of a submission from the holder of the marketing authorisation

dupilumab (Dupixent®) is not recommended for use within NHSScotland.

Indication under review: As an add-on therapy with intranasal corticosteroids for the treatment of adults with severe chronic rhinosinusitis with nasal polyposis for whom therapy with systemic corticosteroids and/or surgery do not provide adequate disease control.

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
dupilumab (Dupixent)
SMC ID:
SMC2324
Indication:

As an add-on therapy with intranasal corticosteroids for the treatment of adults with severe chronic rhinosinusitis with nasal polyposis for whom therapy with systemic corticosteroids and/or surgery do not provide adequate disease control.

Pharmaceutical company
Sanofi Genzyme
BNF chapter
Respiratory system
Submission type
Non submission
Status
Not recommended
Date advice published
18 January 2021