What has SMC said?
The Scottish Medicines Consortium (SMC) has not recommended durvalumab to treat adults with non-small cell lung cancer (NSCLC) that is resectable (can be removed by surgery) but has a high chance of recurrence. Durvalumab is used together with platinum containing chemotherapy as neoadjuvant treatment (treatment to shrink the tumour before surgery) and then by itself as adjuvant treatment (treatment given after surgery to try to stop the cancer coming back).
This document summarises the SMC decision and what it means for patients.
You can find more detailed information about the SMC assessment of durvalumab by looking at the SMC detailed advice document (SMC2677).
What does SMC’s decision mean for patients?
Durvalumab for use as described above should not normally be prescribed on the NHS in Scotland. Your healthcare professional should talk with you about other treatment options.
If your healthcare professional thinks you would benefit from it, they can make a request to prescribe durvalumab. All health boards have procedures in place to consider these requests.
You can find more information about making decisions about your treatment in this booklet called: Medicines in Scotland: What’s the right treatment for me?
More about SMCs decision
SMC was unable to accept durvalumab for routine use. The company's evidence of the medicine’s value for money was not strong enough.
How does SMC make its decision?
SMC carefully considers every new medicine to make sure it benefits patients and is likely to be a good use of NHS resources.
To do this SMC studies the following:
- Evidence from the company about how well the medicine works compared with current treatments available in Scotland, in relation to how much they will cost to buy and use to treat patients.
- Information from patient groups about the potential impact of the medicine on patients and carers.
- Advice from healthcare professionals about any benefits of the new medicine compared to current treatment, along with how the new medicine is likely to be used.
When SMC assesses a medicine it takes account of the needs of all patients in NHSScotland, not only those who may be treated with the medicine.
You can find out more about how SMC decides here: htps://www.scottishmedicines.org.uk/how-we-decide/
More information and support
The organisations below can give more information and support for people with lung cancer and their families. SMC is not responsible for the content of any information provided by external organisations.
Roy Castle Lung Cancer Foundation
0333 323 7200
Scottish Lung Cancer Nurses Forum
You can find out more about durvalumab (brand name: Imfinzi®) in the Patient Information Leaflet (PIL) by searching for the medicine name on the Medicines and Healthcare products Regulatory Agency (MHRA) website.