Advice

following an abbreviated submission

eltrombopag (Revolade®) is accepted for restricted use within NHS Scotland.

Indication under review: chronic immune (idiopathic) thrombocytopenic purpura (ITP) patients aged 1 year to 17 years who are refractory to other treatments (e.g. corticosteroids, immunoglobulins).

SMC restriction: use in patients with severe symptomatic ITP or a high risk of bleeding.

Eltrombopag has previously been accepted for restricted use in adult patients with chronic immune (idiopathic) thrombocytopenic purpura. The license has been extended to include children from 1 year.

SMC advice takes account of the benefits of a Patient Access Scheme (PAS) that improves the cost-effectiveness of eltrombopag. This advice is contingent upon the continuing availability of the PAS in NHS Scotland or a list price that is equivalent or lower.

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Medicine details

Medicine name:
eltrombopag (Revolade)
SMC ID:
1206/17
Indication:
Chronic immune (idiopathic) thrombocytopenic purpura (ITP) patients aged 1 year to 17 years who are refractory to other treatments (e.g. corticosteroids, immunoglobulins).
Pharmaceutical company
Novartis Pharmaceuticals UK Ltd
BNF chapter
Nutrition and blood
Submission type
Abbreviated
Status
Restricted
Date advice published
16 January 2017