Advice

in the absence of a submission from the holder of the marketing authorisation:

enfortumab vedotin (Padcev®) is not recommended for use within NHSScotland.

Indication under review: As monotherapy for the treatment of adult patients with locally advanced or metastatic urothelial cancer who have previously received a platinum-containing chemotherapy and a programmed death receptor-1 or programmed death-ligand 1 inhibitor.

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
enfortumab vedotin (Padcev)
SMC ID:
SMC2505
Indication:

As monotherapy for the treatment of adult patients with locally advanced or metastatic urothelial cancer who have previously received a platinum-containing chemotherapy and a programmed death receptor 1 or programmed death ligand 1 inhibitor.

Pharmaceutical company
Astellas Pharma Ltd
BNF chapter
Malignant disease and immunosuppression
Submission type
Non submission
Status
Not recommended
Date advice published
11 July 2022