Advice

Following a re-submission

Erlotinib (Tarceva®) is accepted for restricted use within NHS Scotland for the treatment of patients with locally advanced or metastatic non-small cell lung cancer, after failure of at least one prior chemotherapy regimen. When prescribing erlotinib, factors associated with prolonged survival should be taken into account. No survival benefit or other clinically relevant effect of the treatment have been demonstrated in patients with epidermal growth factor receptor (EGFR)-negative tumours.

Erlotinib is restricted to use in patients who would otherwise be eligible for treatment with docetaxel monotherapy. No economic case has been made for those whose performance status would make them ineligible to receive docetaxel.

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Medicine details

Medicine name:
Erlotinib (Tarceva®)
SMC ID:
220/05
Indication:
Locally advanced or metastatic non small cell lung cancer after failure of at least one prior chemotherapy regimen
Pharmaceutical company
Roche
BNF chapter
Malignant disease and immunosuppression
Submission type
Resubmission
Status
Superseded
Date advice published
05 June 2006