Advice
Following a full submission
Esomeprazole (Nexium®) is not recommended for use within NHS Scotland for the prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory (NSAID) therapy in patients at risk.
When compared to placebo, esomeprazole reduces the rate of gastro-duodenal ulcers associated with NSAID therapy in at-risk patients. There are no comparisons of esomeprazole with other proton pump inhibitors for this indication. The economic case has not been demonstrated.
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Medicine details
- Medicine name:
- Esomeprazole (Nexium®)
- SMC ID:
- 257/06
- Indication:
- Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory (NSAID) therapy
- Pharmaceutical company
- AstraZeneca UK Ltd
- BNF chapter
- Gastro-intestinal system
- Submission type
- Full
- Status
- Not recommended
- Date advice published
- 12 June 2006