Advice

Following a full submission

Esomeprazole (Nexium®) is not recommended for use within NHS Scotland for the healing of gastric ulcers associated with non-steroidal anti-inflammatory drug (NSAID) therapy.

In the treatment of gastric ulcers associated with NSAID therapy, esomeprazole produced greater healing rates than a histamine-H2 antagonist. However, there are no comparisons of esomeprazole with other proton pump inhibitors for this indication. The economic case has not been demonstrated.

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Medicine details

Medicine name:
Esomeprazole (Nexium®)
SMC ID:
274/06
Indication:
Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug (NSAID) therapy,
Pharmaceutical company
AstraZeneca UK Ltd
BNF chapter
Gastro-intestinal system
Submission type
Full
Status
Not recommended
Date advice published
12 June 2006