Advice

Following a full submission

glucosamine (as hydrochloride) (Alateris) is not recommended for use within NHS Scotland for relief of symptoms in mild to moderate osteoarthritis of the knee.

No direct clinical trial evidence of the efficacy and safety of this specific product is available.

Randomised controlled trials of other formulations of glucosamine hydrochloride indicate little or no benefit over placebo in improving symptoms in patients with osteoarthritis of the knee.

In addition, the manufacturer did not present a sufficiently robust economic analysis to gain acceptance by SMC.

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Medicine details

Medicine name:
glucosamine (Alateris)
SMC ID:
471/08
Indication:
Relief of symptoms in mild to moderate osteoarthritis of the knee
Pharmaceutical company
William Ransom and Son plc
BNF chapter
Musculoskeletal and joint diseases
Submission type
Full
Status
Not recommended
Date advice published
09 June 2008