Advice
Following a third resubmission
glyceryl trinitrate 0.4% ointment (Rectogesic®) is not recommended for use within NHS Scotland for relief of pain associated with chronic anal fissure.
It was associated with very small improvements in pain scores compared with vehicle, and therefore little clinically significant effect.
The manufacturer did not present a sufficiently robust economic case to gain acceptance by SMC.
Download detailed advice94KB (PDF)
Medicine details
- Medicine name:
- glyceryl trinitrate 0.4% (Rectogesic)
- SMC ID:
- 200/05
- Indication:
- Relief of pain associated with chronic anal fissure
- Pharmaceutical company
- ProStrakan
- BNF chapter
- Gastro-intestinal system
- Submission type
- Resubmission
- Status
- Not recommended
- Date advice published
- 11 February 2008