Advice

Following a third resubmission

glyceryl trinitrate 0.4% ointment (Rectogesic®) is not recommended for use within NHS Scotland for relief of pain associated with chronic anal fissure.

It was associated with very small improvements in pain scores compared with vehicle, and therefore little clinically significant effect.

The manufacturer did not present a sufficiently robust economic case to gain acceptance by SMC.

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Medicine details

Medicine name:
glyceryl trinitrate 0.4% (Rectogesic)
SMC ID:
200/05
Indication:
Relief of pain associated with chronic anal fissure
Pharmaceutical company
ProStrakan
BNF chapter
Gastro-intestinal system
Submission type
Resubmission
Status
Not recommended
Date advice published
11 February 2008