Advice

in the absence of a submission from the holder of the marketing authorisation:

ibrutinib (Imbruvica®) is not recommended for use within NHS Scotland.

Indication under review: In combination with bendamustine and rituximab for the treatment of adult patients with chronic lymphocytic leukaemia who have received at least one prior therapy.

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this setting.  As a result we cannot recommend its use within NHSScotland.

Download detailed advice68KB (PDF)

Download

Medicine details

Medicine name:
ibrutinib (Imbruvica)
SMC ID:
1258/17
Indication:
In combination with bendamustine and rituximab for the treatment of adult patients with chronic lymphocytic leukaemia who have received at least one prior therapy.
Pharmaceutical company
Janssen-Cilag Ltd
BNF chapter
Malignant disease and immunosuppression
Submission type
Non submission
Status
Not recommended
Date advice published
12 June 2017