Advice

following a full submission:

insulin glargine/lixisenatide (Suliqua®) is accepted for restricted use within NHSScotland.

Indication under review: In combination with metformin for the treatment of adults with type 2 diabetes mellitus, to improve glycaemic control when this has not been provided by metformin alone or metformin combined with another oral glucose-lowering medicinal product or with basal insulin.

SMC restriction: for use in patients who are uncontrolled on basal insulin (glycosylated haemoglobin [HbA1c] > 7.5% [59mmol/mol]) and for whom a GLP-1 receptor agonist is appropriate as an add-on intensification therapy to basal insulin analogues.

Insulin glargine/lixisenatide improved glycaemic control compared with insulin glargine alone in adults with inadequately controlled type 2 diabetes mellitus.

Medicine details

Medicine name:
insulin glargine/lixisenatide (Suliqua)
SMC ID:
SMC2235
Indication:

In combination with metformin for the treatment of adults with type II diabetes mellitus (T2DM), to improve glycaemic control when this has not been provided by metformin alone or metformin combined with another oral glucose-lowering medicinal product or with basal insulin.

Pharmaceutical company
Sanofi-Aventis
BNF chapter
Endocrine system
Submission type
Full
Status
Restricted
Date advice published
13 April 2020