Advice

Following a full submission

interferon beta-1b (Betaferon) is not recommended for use within NHS Scotland for the treatment of patients with a single demyelinating event with an active inflammatory process, severe enough to warrant treatment with intravenous corticosteroids, where alternative diagnoses are excluded and who are determined to be at high risk of developing clinically definite multiple sclerosis.

Although interferon beta-1b has been found to increase the time to clinically definite multiple sclerosis over 2 years, the long-term effect on the disease process remains unknown. The economic case has not been demonstrated.

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Medicine details

Medicine name:
Interferon beta-1b 250microgram/ml for solution for injection (Betaferon)
SMC ID:
345/07
Indication:
Multiple sclerosis
Pharmaceutical company
Schering Health Care Ltd
BNF chapter
Malignant disease and immunosuppression
Submission type
Full
Status
Not recommended
Date advice published
12 February 2007