following a resubmission:
iron III isomaltoside 1000 5% (Diafer®) is accepted for use within NHS Scotland.
Indication under review: For the treatment of iron deficiency in adults with chronic kidney disease (CKD) on dialysis, when oral iron preparations are ineffective or cannot be used.
Iron III isomaltoside 1000 at a higher (10%) concentration has been shown to be non-inferior to another intravenous iron product in maintaining haemoglobin concentration in adult patients with CKD who are iron deficient and are receiving haemodialysis.
This SMC advice takes account of the benefits of a Patient Access Scheme (PAS) that improves the cost-effectiveness of iron III isomaltoside 1000 5%. This advice is contingent upon the continuing availability of the PAS in NHS Scotland or a list price that is equivalent or lower.
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Medicine details
- Medicine name:
- iron (III) isomaltoside 1000 (Diafer)
- SMC ID:
- 1177/16
- Indication:
- For the treatment of iron deficiency in adults with chronic kidney disease (CKD) on dialysis, when oral iron preparations are ineffective or cannot be used.
- Pharmaceutical company
- Pharmacosmos UK
- BNF chapter
- Nutrition and blood
- Submission type
- Resubmission
- Status
- Accepted
- Date advice published
- 13 February 2017