Advice

Following a resubmission

levetiracetam (Keppra) is accepted for use within NHS Scotland as adjunctive therapy in the treatment of primary generalised tonic-clonic seizures in adults and adolescents from 12 years of age with generalised idiopathic epilepsy.

In the pivotal study, addition of levetiracetam to existing anticonvulsant therapy achieved a significantly greater reduction in the frequency of primary generalised tonic-clonic seizures than addition of placebo.

Download detailed advice87KB (PDF)

Download

Medicine details

Medicine name:
levetiracetam 250 500 750 and 1000mg tablets and levetiracetam oral solution 100mg/ml (Keppra)
SMC ID:
396/07
Indication:
adjunctive therapy in treatment of primary generalised tonic-clonic seizures in adults and adolescents from 12 years of age with generalised idiopathic epilepsy
Pharmaceutical company
UCB Pharma Ltd
BNF chapter
Central nervous system
Submission type
Resubmission
Status
Accepted
Date advice published
11 February 2008