Advice

Following a full submission

Cytarabine liposomal suspension for injection (Depocyte) is not recommended for use within NHS Scotland for the intrathecal treatment of lymphomatous meningitis.

Intrathecally administered cytarabine liposomal suspension cleared malignant cells from the cerebrospinal fluid, however effects on symptom improvement were not well defined and the cost-effectiveness compared to cytarabine solution has not been demonstrated.

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Medicine details

Medicine name:
liposomal cytarabine 50mg suspension for injection (Depocyte®)
SMC ID:
164/05
Indication:
Intrathecal treatment of lymphomatous meningitis
Pharmaceutical company
Napp Pharmaceuticals Ltd
BNF chapter
Malignant disease and immunosuppression
Submission type
Full
Status
Not recommended
Date advice published
09 May 2005