Advice

following a full submission

lixisenatide (Lyxumia®) is accepted for restricted use within NHS Scotland.

Indication under review: treatment of adults with type 2 diabetes mellitus to achieve glycaemic control in combination with oral glucose-lowering medicinal products and/or basal insulin when these, together with diet and exercise, do not provide adequate glycaemic control.
SMC restriction: to use in patients for whom a glucagon-like protein-1 (GLP-1) agonist is appropriate, as an alternative to existing GLP-1 agonists.

Lixisenatide reduces glycosylated haemoglobin (HbA1c) and body weight compared with placebo when used in combination with oral antidiabetic drugs or in combination with basal insulin.

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Medicine details

Medicine name:
lixisenatide (Lyxumia)
SMC ID:
903/13
Indication:
Treatment of adults with type 2 diabetes mellitus to achieve glycaemic control in combination with oral glucose-lowering medicinal products and/or basal insulin when these, together with diet and exercise, do not provide adequate glycaemic control.
Pharmaceutical company
Sanofi-Aventis
BNF chapter
Endocrine system
Submission type
Full
Status
Restricted
Date advice published
09 September 2013