Advice

following a full submission:

lurasidone (Latuda®) is accepted for restricted use within NHS Scotland.

Indication under review: For the treatment of schizophrenia in adults aged 18 years and over.

SMC Restriction: as an alternative treatment option in patients in whom it is important to avoid weight gain and metabolic adverse effects.

Lurasidone demonstrated benefit over placebo in mean change from baseline in Positive and Negative Syndrome Scale (PANSS) total score after six weeks of treatment and was non-inferior to another second generation antipsychotic medicine for time to relapse over 12 months.
 

Download detailed advice197KB (PDF)

Download

Medicine details

Medicine name:
lurasidone (Latuda)
SMC ID:
994/14
Indication:
For the treatment of schizophrenia in adults aged 18 years and over.
Pharmaceutical company
Sunovion
BNF chapter
Central nervous system
Submission type
Full
Status
Restricted
Date advice published
13 October 2014