Advice

following an abbreviated submission:

medroxyprogesterone acetate injection (Sayana® Press) is accepted for use within NHS Scotland.

Indication under review: for long-term female contraception.  Each subcutaneous injection prevents ovulation and provides contraception for at least 13 weeks (+/- 1 week).  However, it should be taken into consideration that the return to fertility (ovulation) may be delayed for up to one year.

In adolescents (12-18years), use of medroxyprogesterone acetate injection is only indicated when other contraceptive methods are considered unsuitable or unacceptable, due to unknown long-term effects of bone loss associated with medroxyprogesterone acetate injection during the critical period of bone accretion.

Sayana® Press contains medroxyprogesterone acetate for subcutaneous injection at a similar cost to the existing deep intramuscular injection.

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Medicine details

Medicine name:
medroxyprogesterone acetate (Sayana Press)
SMC ID:
896/13
Indication:
For long-term female contraception. Each subcutaneous injection prevents ovulation and provides contraception for at least 13 weeks (+/- 1 week). However, it should be taken into consideration that the return to fertility (ovulation) may be delayed for up to one year.
Pharmaceutical company
Pfizer Ltd
BNF chapter
Endocrine system
Submission type
Abbreviated
Status
Accepted
Date advice published
09 September 2013