Advice

in the absence of a submission from the holder of the marketing authorisation:

mepolizumab (Nucala®) is not recommended for use within NHSScotland.

Indication under review: As an add-on therapy with intranasal corticosteroids for the treatment of adult patients with severe chronic rhinosinusitis with nasal polyps for whom therapy with systemic corticosteroids and/or surgery do not provide adequate control.

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
mepolizumab (Nucala)
SMC ID:
SMC2491
Indication:

As an add-on therapy with intranasal corticosteroids for the treatment of adult patients with severe chronic rhinosinusitis with nasal polyps for whom therapy with systemic corticosteroids and/or surgery do not provide adequate control.

Pharmaceutical company
GlaxoSmithKline UK Ltd
BNF chapter
Ear, nose and oropharynx
Submission type
Non submission
Status
Not recommended
Date advice published
09 May 2022