Advice
Following a re-submission
Metformin hydrochloride prolonged-release (Glucophage SR®) is not recommended for use within NHS Scotland for the treatment of adults with type-2 diabetes.
This new formulation appears to have similar short-term efficacy to immediate-release metformin. Evidence of improved gastrointestinal tolerability is not convincing and the prolonged-release formulation is more expensive than the immediate-release formulation.
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Medicine details
- Medicine name:
- Metformin hydrochloride (Glucophage SR®)
- SMC ID:
- 148/04
- Indication:
- Type-2 diabetes mellitus
- Pharmaceutical company
- Merck Serono Ltd
- BNF chapter
- Endocrine system
- Submission type
- Resubmission
- Status
- Not recommended
- Date advice published
- 09 January 2006