Advice

following a full submission:

naldemedine (Rizmoic®) is accepted for use within NHSScotland.

Indication under review: For the treatment of opioid-induced constipation (OIC) in adult patients who have previously been treated with a laxative.

Naldemedine compared to placebo significantly improved the spontaneous bowel movement response rate in patients with opioid-induced constipation and either non-cancer or cancer pain.

Medicine details

Medicine name:
naldemedine (Rizmoic)
SMC ID:
SMC2242
Indication:

For the treatment of opioid-induced constipation (OIC) in adult patients who have previously been treated with a laxative.

Pharmaceutical company
Shionogi Limited
BNF chapter
Gastro-intestinal system
Submission type
Full
Status
Accepted
Date advice published
13 April 2020