Advice

following a resubmission considered under the end of life / orphan medicine process:

paclitaxel albumin (Abraxane®) is accepted for use within NHS Scotland.

Indication under review: in combination with gemcitabine for the first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas.

In a randomised, phase III, open-label study paclitaxel albumin plus gemcitabine treatment improved median overall survival by 1.8 months compared with gemcitabine alone.

This advice takes account of the views from a Patient and Clinician Engagement (PACE) meeting.

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Medicine details

Medicine name:
paclitaxel albumin (Abraxane)
SMC ID:
968/14
Indication:
In combination with gemcitabine for the first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas.
Pharmaceutical company
Celgene Ltd
BNF chapter
Malignant disease and immunosuppression
Submission type
Resubmission
Status
Accepted
Date advice published
09 February 2015