Advice

Following a full submission.

Palonosetron (Aloxi) is accepted for use within NHS Scotland for the prevention of acute nausea and vomiting associated with highly emetogenic cancer chemotherapy and the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy.

It is as effective as other 5HT3 antagonists in preventing emesis when given as a single intravenous injection following highly emetogenic chemotherapy (HEC) in the acute phase and moderately emetogenic chemotherapy (MEC) in the acute and delayed phases post–chemotherapy.

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Medicine details

Medicine name:
Palonosetron 250 micrograms solution for injection (Aloxi®)
SMC ID:
208/05
Indication:
Prevention of acute nausea and vomiting associated with highly-emetogenic cancer chemotherapy and the prevention of nausea and vomiting associated with moderately -emetogenic cancer chemotherapy
Pharmaceutical company
Cambridge Laboratories
BNF chapter
Central nervous system
Submission type
Full
Status
Accepted
Date advice published
07 November 2005