Advice

Parecoxib is not recommended for use within NHS Scotland.

RECOMMENDATION.

There is no evidence that the parenteral COX-2 selective non-steroidal anti-inflammatory drug (NSAID), parecoxib, is associated with a reduction in clinically significant post-operative haemorrhagic or gastro-intestinal complications compared with the non-selective NSAIDs. Parecoxib is substantially more expensive than non selective NSAIDs and should therefore not replace these drugs.

The license holder has indicated their decision to resubmit in light of additional information.

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Medicine details

Medicine name:
Parecoxib (Dynastat®)
SMC ID:
27/02
Indication:
Short-term treatment of postoperative pain
Pharmaceutical company
Pharmacia
BNF chapter
Musculoskeletal and joint diseases
Submission type
Full
Status
Not recommended
Date advice published
10 January 2003