Advice
in the absence of a submission from the holder of the marketing authorisation:
pegzilarginase (Loargys)®) is not recommended for use within NHSScotland.
Indication under review: treatment of arginase 1 deficiency (ARG1-D), also known as hyperargininemia, in adults, adolescents and children aged 2 years and older.
The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication.
As a result, we cannot recommend its use within NHSScotland.
Download detailed advice240KB (PDF)
Medicine details
- Medicine name:
- pegzilarginase (Loargys)
- SMC ID:
- SMC2813
- Indication:
Treatment of arginase 1 deficiency (ARG1-D), also known as hyperargininemia, in adults, adolescents and children aged 2 years and older.
- Pharmaceutical company
- Immedica
- BNF chapter
- Nutrition and blood
- Submission type
- Non submission
- Status
- Not recommended
- Date advice published
- 09 June 2025