Advice

Medicine discontinued

In September, 2024, the Marketing Authorisation for pralsetinib (Gavreto) was discontinued. 

Medicine details

Medicine name:
pralsetinib (Gavreto)
SMC ID:
SMC2496
Indication:

As monotherapy for the treatment of adult patients with rearranged during transfection (RET) fusion-positive advanced non-small cell lung cancer (NSCLC) not previously treated with a RET inhibitor.

Pharmaceutical company
Roche
BNF chapter
Malignant disease and immunosuppression
Submission type
Full
Status
Withdrawn
Date advice published
13 March 2023
Additional notes

In September, 2024, the Marketing Authorisation for pralsetinib (Gavreto) moved from Roche to BluePrint Medicines. BluePrint Medicines will discontinue global marketing and development of pralsetinib in all territories (excluding US and Greater China).