What has SMC said?
The Scottish Medicines Consortium (SMC) has accepted quizartinib to treat adults with newly diagnosed acute myeloid leukaemia (AML; a type of blood cancer), where the cancer is FLT3-ITD positive (the cancer cells have a certain mutation in the gene for a protein called FLT3). Quizartinib is used with cytarabine and anthracycline induction chemotherapy (chemotherapy used at the start of treatment) and then together with cytarabine for consolidation chemotherapy. Then quizartinib is used on its own as a maintenance treatment.
This document summarises the SMC decision and what it means for patients.
You can find more detailed information about the SMC assessment of quizartinib by looking at the SMC detailed advice document (SMC2699).
What does SMC’s decision mean for patients?
Quizartinib for use as described above is available for prescribing on the NHS in Scotland. Your healthcare professional can discuss with you if it is the right treatment for you.
You can find more information about making decisions about your treatment in this booklet called: Medicines in Scotland: What’s the right treatment for me?
More about SMCs decision
SMC’s decision takes into account a confidential discount offered by the pharmaceutical company.
How does SMC make its decision?
SMC carefully considers every new medicine to make sure it benefits patients and is likely to be a good use of NHS resources.
To do this SMC studies the following:
- Evidence from the company about how well the medicine works compared with current treatments available in Scotland, in relation to how much they will cost to buy and use to treat patients.
- Information from patient groups about the potential impact of the medicine on patients and carers.
- Advice from healthcare professionals about any benefits of the new medicine compared to current treatment, along with how the new medicine is likely to be used.
When SMC assesses a medicine it takes account of the needs of all patients in NHSScotland, not only those who may be treated with the medicine.
You can find out more about how SMC decides here: htps://www.scottishmedicines.org.uk/how-we-decide/
More information and support
The organisations below can give more information and support for people with leukaemia and their families. SMC is not responsible for the content of any information provided by external organisations.
Blood Cancer UK
0808 2080 888
Leukaemia Care
https://www.leukaemiacare.org.uk
0808 801 0444
You can find out more about quizartinib (brand name: Vanflyta®) in the Patient Information Leaflet (PIL) by searching for the medicine name on the Medicines and Healthcare products Regulatory Agency (MHRA) website.