Advice

in the absence of a submission from the holder of the marketing authorisation:

ramucirumab (Cyramza®) is not recommended for use within NHS Scotland.

Indications under review:

  • In combination with paclitaxel for the treatment of adult patients with advanced gastric cancer or gastro-oesophageal junction adenocarcinoma with disease progression after prior platinum and fluoropyrimidine chemotherapy
  • As monotherapy for the treatment of adult patients with advanced gastric cancer or gastro-oesophageal junction adenocarcinoma with disease progression after prior platinum or fluoropyrimidine chemotherapy, for whom treatment in combination with paclitaxel is not appropriate

The holder of the marketing authorisation has not made a submission to SMC regarding this product in these indications.  As a result we cannot recommend its use within NHSScotland.

Download detailed advice111KB (PDF)

Download

Medicine details

Medicine name:
ramucirumab (Cyramza)
SMC ID:
1176/16
Indication:
In combination with paclitaxel for the treatment of adult patients with advanced gastric cancer or gastro-oesophageal junction adenocarcinoma with disease progression after prior platinum and fluoropyrimidine chemotherapy As monotherapy for the treatment of adult patients with advanced gastric cancer or gastro-oesophageal junction adenocarcinoma with disease progression after prior platinum or fluoropyrimidine chemotherapy, for whom treatment in combination with paclitaxel is not appropriate
Pharmaceutical company
Eli Lilly and Company Ltd
BNF chapter
Malignant disease and immunosuppression
Submission type
Non submission
Status
Not recommended
Date advice published
11 July 2016