Advice

following a full submission:

relugolix, estradiol, norethisterone acetate film-coated tablets (Ryeqo®) is accepted for use within NHSScotland.

Indication under review: in adult women of reproductive age for symptomatic treatment of endometriosis in women with a history of previous medical or surgical treatment for their endometriosis.

Relugolix, estradiol, norethisterone acetate film-coated tablets (Ryeqo®), compared with placebo, resulted in statistically and clinically significant improvements in treatment response (menstrual and non-menstrual pelvic pain) after 24 weeks in women with moderate-to-severe pain associated with endometriosis.

Medicine details

Medicine name:
relugolix / estradiol / norethisterone acetate (Ryeqo)
SMC ID:
SMC2666
Indication:

In adult women of reproductive age for symptomatic treatment of endometriosis in women with a history of previous medical or surgical treatment for their endometriosis.

Pharmaceutical company
Gedeon Richter UK Ltd
BNF chapter
Obstetrics, gynaecology, and urinary-tract disorders
Submission type
Full
Status
Accepted
Date advice published
13 January 2025