Advice
following a full submission:
 
rivaroxaban (Xarelto®) is accepted for use within NHS Scotland.
 
Indication under review: treatment of deep vein thrombosis (DVT), and prevention of recurrent DVT and pulmonary embolism (PE) following an acute DVT in adults.
 
Rivaroxaban has been shown to be non-inferior to standard anticoagulant therapy including a low molecular weight heparin in combination with a vitamin K antagonist for the treatment of proximal DVT and prevention of recurrence.
 
Experience with rivaroxaban in this indication for more than 12 months is limited therefore the cost-effectiveness of indefinite treatment has not been demonstrated.

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Medicine details

Medicine name:
rivaroxaban (Xarelto) DVT
SMC ID:
755/12
Indication:
For the treatment of DVT and prevention of recurrent DVT & pulmonary embolism following acute DVT in adults
Pharmaceutical company
Bayer plc/Bayer Schering Pharma
BNF chapter
Cardiovascular system
Submission type
Full
Status
Accepted
Date advice published
13 February 2012